Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462612 | 0.87 | TRPA1 (0.51) | KDM4ENR4A2TRPA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7462376 | 0.87 | ALDH1A1 (0.49) | KDM4ENR4A2MAPTARSMN1; SMN2 | |
| SCHEMBL7461265 | 0.87 | KDM4E (0.45) | KDM4ENR4A2TRPA1ARSMN1; SMN2 | |
| SCHEMBL7465295 | 0.82 | KDM4E (0.58) | KDM4ENR4A2TRPA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7465640 | 0.82 | NR4A2 (0.42) | KDM4ENR4A2MAPTTRPA1AR | |
| SCHEMBL7531657 | 0.82 | NR4A2 (0.59) | KDM4ENR4A2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7044612 | 0.80 | NR4A2 (0.45) | KDM4ENR4A2MAPTTRPA1SMN1; SMN2 | |
| SCHEMBL7467276 | 0.78 | NR4A2 (0.43) | KDM4ENR4A2MAPTTRPA1SMN1; SMN2 | |
| SCHEMBL7458647 | 0.78 | NR4A2 (0.43) | KDM4ENR4A2MAPTARSMN1; SMN2 | |
| SCHEMBL18118619 | 0.77 | NR4A2 (0.45) | KDM4ENR4A2MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |