Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044612 | 0.88 | NR4A2 (0.45) | NR4A2HTTMAPTKDM4ETRPA1 | |
| SCHEMBL7462376 | 0.87 | ALDH1A1 (0.49) | NR4A2HTTMAPTTDP1L3MBTL1 | |
| SCHEMBL7462612 | 0.87 | TRPA1 (0.51) | NR4A2L3MBTL1KDM4ETRPA1SMN1; SMN2 | |
| SCHEMBL7458647 | 0.86 | NR4A2 (0.43) | NR4A2HTTMAPTTDP1KDM4E | |
| SCHEMBL7467276 | 0.86 | NR4A2 (0.43) | NR4A2HTTMAPTGAAKDM4E | |
| SCHEMBL7471877 | 0.85 | NR4A2 (0.47) | NR4A2HTTMAPTGAATDP1 | |
| SCHEMBL18796134 | 0.84 | NR4A2 (0.41) | NR4A2HTTMAPTKDM4ETRPA1 | |
| SCHEMBL7465356 | 0.82 | KDM4E (0.43) | NR4A2HTTMAPTKDM4ETRPA1 | |
| SCHEMBL7531657 | 0.82 | NR4A2 (0.59) | NR4A2HTTMAPTGAATDP1 | |
| SCHEMBL7461347 | 0.80 | GAA (0.54) | HTTMAPTGAATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |