Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 17/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221837 | 1.00 | ADORA3 (0.48) | ADORA3ADORA2AADORA1ADORA2BHTR2C | |
| SCHEMBL7221838 | 0.95 | ADORA3 (0.48) | ADORA3ADORA2AADORA1ADORA2BHTR2C | |
| SCHEMBL7224964 | 0.93 | PGK1 (0.45) | ADORA3ADORA2AADORA1ADORA2B | |
| Formic Acid SCHEMBL7221833 | 0.92 | ADORA3 (0.55) | ADORA3ADORA2AADORA1ADORA2BHTR2C | |
| SCHEMBL7465380 | 0.91 | ADORA3 (0.58) | ADORA3ADORA2AADORA1ADORA2BHTR2C | |
| SCHEMBL7230202 | 0.90 | PGK1 (0.50) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7224970 | 0.88 | PGK1 (0.46) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7224024 | 0.86 | ADORA2A (0.41) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7459716 | 0.86 | ADORA2A (0.44) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7223843 | 0.86 | ADORA2A (0.44) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948509-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-16 | — | — | EP | disclosed |