Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6424007 | 0.85 | NSD2 (0.43) | SNCANSD2EPHX2SIGMAR1TMEM97 | |
| SCHEMBL1009189 | 0.80 | NSD2 (0.45) | SNCANSD2EPHX2CHRM2CHRM1 | |
| SCHEMBL7401773 | 0.76 | HTT (0.51) | SNCANSD2SIGMAR1TMEM97MMP12 | |
| SCHEMBL7465397 | 0.73 | TSHR (0.44) | NSD2EPHX2MAOBPOLBMAPT | |
| SCHEMBL18677419 | 0.72 | PPARA (0.48) | PPARAPPARDEPHX2MMP12MMP13 | |
| SCHEMBL23013509 | 0.71 | XDH (0.38) | — | |
| SCHEMBL7233237 | 0.70 | NSD2 (0.53) | PPARAPPARDSNCANSD2EPHX2 | |
| SCHEMBL17701291 | 0.69 | NSD2 (0.48) | SNCANSD2EPHX2SIGMAR1TMEM97 | |
| SCHEMBL18301296 | 0.69 | CACNA1H (0.38) | — | |
| SCHEMBL5028368 | 0.69 | HRH3 (0.45) | PPARAPPARDNSD2EPHX2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000032574-A1 | NOVEL 2-PYRIDONE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-06-08 | — | — | WO | disclosed |