Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474806 | 0.90 | EGFR (0.52) | EGFRALDH1A1MAPK1KDM4EMAPT | |
| SCHEMBL7463424 | 0.88 | EGFR (0.50) | EGFRALDH1A1MAPK1KDM4EKMT2A | |
| SCHEMBL7474842 | 0.87 | RXFP1 (0.62) | EGFRALDH1A1MAPK1KDM4ERXFP1 | |
| SCHEMBL7469892 | 0.86 | EGFR (0.55) | EGFRALDH1A1MAPK1KDM4ERXFP1 | |
| SCHEMBL7470465 | 0.85 | MAPK1 (0.66) | EGFRALDH1A1MAPK1KDM4EKMT2A | |
| SCHEMBL7475194 | 0.84 | EGFR (0.66) | EGFRMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL7460787 | 0.83 | EGFR (0.51) | EGFRMAPK1AURKARPS6KB1 | |
| SCHEMBL7461665 | 0.83 | USP10 (0.59) | EGFRMAPK1KMT2AMEN1 | |
| SCHEMBL7469106 | 0.82 | CLK4 (0.58) | EGFRMAPK1AURKARPS6KB1 | |
| SCHEMBL7469700 | 0.82 | EGFR (0.54) | EGFRALDH1A1MAPK1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |