Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 8/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | USP2 | O75604 | 6/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465156 | 0.90 | MAPK1 (0.53) | MAPK1ALDH1A1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL7474842 | 0.87 | RXFP1 (0.62) | MAPK1ALDH1A1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL8825801 | 0.86 | MAPK1 (0.64) | MAPK1ALDH1A1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL7465660 | 0.85 | EGFR (0.56) | MAPK1ALDH1A1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL7473060 | 0.84 | STAT1 (0.64) | MAPK1ALDH1A1KDM4ESMN1; SMN2EGFR | |
| SCHEMBL7469892 | 0.84 | EGFR (0.55) | MAPK1ALDH1A1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL7470701 | 0.83 | PDE5A (0.56) | MAPK1ALDH1A1KDM4EEGFRLMNA | |
| SCHEMBL7475194 | 0.82 | EGFR (0.66) | MAPK1KDM4ESMN1; SMN2EGFRLMNA | |
| SCHEMBL7474668 | 0.82 | HTT (0.63) | MAPK1ALDH1A1KDM4ESMN1; SMN2EGFR | |
| SCHEMBL7470418 | 0.81 | MAPK1 (0.65) | MAPK1ALDH1A1SMN1; SMN2EGFRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |