Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474806 | 0.91 | EGFR (0.52) | EGFRMAPK1KDM4EALDH1A1HTT | |
| SCHEMBL7465156 | 0.88 | MAPK1 (0.53) | EGFRMAPK1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7474181 | 0.88 | MAPK1 (0.56) | EGFRMAPK1HTTMAPTPIK3CD | |
| SCHEMBL7461530 | 0.85 | PKM (0.56) | EGFRMAPK1KDM4EALDH1A1HTT | |
| SCHEMBL7463424 | 0.85 | EGFR (0.50) | EGFRMAPK1KDM4EALDH1A1PRKCQ | |
| SCHEMBL7457697 | 0.84 | EGFR (0.62) | EGFRMAPT | |
| SCHEMBL7471567 | 0.84 | PIK3CD (0.62) | EGFRMAPK1HTTMAPTPIK3CD | |
| SCHEMBL7469664 | 0.83 | HTT (0.63) | EGFRMAPK1HTTMAPTPIK3CD | |
| SCHEMBL7468426 | 0.83 | WDR5 (0.42) | EGFRMAPK1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7462734 | 0.83 | EGFR (0.55) | EGFRMAPK1HTTMAPTPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |