Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628272 | 0.86 | GABRA1 (0.40) | PNMTTAAR1HTR2A | |
| SCHEMBL12935970 | 0.84 | PNMT (0.33) | PNMT | |
| SCHEMBL5953538 | 0.80 | HTR2A (0.42) | PNMTHTR2A | |
| SCHEMBL3686997 | 0.78 | HTR2A (0.43) | PNMTHTR2A | |
| SCHEMBL5954073 | 0.76 | BCHE (0.36) | — | |
| SCHEMBL4035804 | 0.76 | CYP2A6 (0.36) | — | |
| SCHEMBL30477217 | 0.76 | CYP2A6 (0.36) | — | |
| SCHEMBL5953854 | 0.73 | SIGMAR1 (0.39) | HTR2A | |
| SCHEMBL7464131 | 0.73 | — | — | |
| SCHEMBL7093971 | 0.73 | CYP11B1 (0.36) | PNMTTAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369254-B1 | COORDINATION CATALYST FOR POLYMERIZATION CATALYSTS | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-04-09 | — | — | US | disclosed |
| EP-0846122-B1 | BRIDGED METALLOCENE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-07-05 | — | — | EP | disclosed |
| EP-0846122-A1 | BRIDGED METALLOCENE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Montell Technology Company B.V. (NL) | 1998-06-10 | — | — | EP | disclosed |
| WO-1996038458-A1 | BRIDGED METALLOCENE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1996-12-05 | — | — | WO | disclosed |