Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953854 | 0.83 | SIGMAR1 (0.39) | HTR2ASMN1; SMN2CYP2D6NPSR1DRD2 | |
| SCHEMBL5953689 | 0.82 | HTR2A (0.39) | HTR2ACALM1BCL2BCL2L1SMN1; SMN2 | |
| SCHEMBL7465941 | 0.80 | PNMT (0.35) | HTR2APNMT | |
| SCHEMBL7628272 | 0.78 | GABRA1 (0.40) | HTR2ACYP2D6MEN1KMT2APNMT | |
| SCHEMBL5953551 | 0.77 | HTR2A (0.36) | HTR2ACALM1BCL2BCL2L1SMN1; SMN2 | |
| SCHEMBL5954058 | 0.75 | HTR2A (0.41) | HTR2ACALM1BCL2BCL2L1CYP3A4 | |
| SCHEMBL7861886 | 0.71 | CALM1 (0.52) | HTR2ACALM1BCL2BCL2L1SMN1; SMN2 | |
| SCHEMBL6905933 | 0.69 | HTR2A (0.41) | HTR2ACALM1BCL2BCL2L1SMN1; SMN2 | |
| SCHEMBL1827132 | 0.69 | PDCD1 (0.39) | BCL2L1HPGDKMT2ATSHR | |
| SCHEMBL30229874 | 0.69 | PDCD1 (0.39) | BCL2L1HPGDKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052620-A1 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2006-03-09 | — | — | US | disclosed |
| EP-1492749-A1 | PREPARATION OF SUBSTITUTED INDENES | Basell Polyolefine GmbH (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084904-A1 | PREPARATION OF SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |
| EP-1150986-A4 | SILYL AMINES | BOULDER SCIENT CO (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1150986-A1 | SILYL AMINES | BOULDER SCIENTIFIC COMPANY (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2001038334-A1 | SILYL AMINES | BOULDER SCIENTIFIC COMPANY (US) | 2001-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052620-A1 | Preparation of substituted indenes | INTS9, CYP1A2, INF2 | HTR2A 3428/4885CALM1 3779/4885BCL2 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.