Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489175 | 0.90 | CYP1A2 (0.42) | CYP1A2PTGDR2MEN1KMT2AALDH1A1 | |
| SCHEMBL8489171 | 0.90 | CYP1A2 (0.42) | CYP1A2PTGDR2MEN1KMT2AALDH1A1 | |
| SCHEMBL27958906 | 0.84 | HSPB1 (0.43) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL5492543 | 0.83 | ALDH1A1 (0.46) | CYP1A2PTGDR2RAB9AMEN1KMT2A | |
| SCHEMBL2995971 | 0.82 | CYP1A2 (0.42) | CYP1A2PTGDR2RAB9AMEN1KMT2A | |
| SCHEMBL2993623 | 0.82 | RAB9A (0.47) | CYP1A2PTGDR2RAB9AMEN1KMT2A | |
| SCHEMBL20299852 | 0.79 | BCL9 (0.46) | RAB9AMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9226719 | 0.78 | TSHR (0.49) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7465971 | 0.78 | RAB9A (0.41) | CYP1A2PTGDR2RAB9AMEN1KMT2A | |
| SCHEMBL7603979 | 0.78 | MEN1 (0.47) | CYP1A2PTGDR2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032481-A1 | MUSCARINIC AGENTS AND USE THEREOF TO TREAT GLAUCOMA, MYOPIA AND VARIOUS OTHER CONDITIONS | ALCON LABORATORIES, INC. (US) | 1999-07-01 | — | — | WO | disclosed |