Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4991862 | 0.92 | CARM1 (0.48) | PTGER4SCN4APTGER2FAAHHSPB1 | |
| SCHEMBL4995320 | 0.88 | SCN9A (0.49) | PTGER4SCN9A | |
| SCHEMBL4989136 | 0.85 | CYP3A4 (0.48) | PTGER4SCN4APTGER2FAAHPARP10 | |
| SCHEMBL7455699 | 0.82 | ACACB (0.47) | PTGER4PTGER2CARM1PRMT6PNLIP | |
| SCHEMBL7460324 | 0.82 | LTA4H (0.42) | PTGER4SCN4APTGER2CARM1PRMT6 | |
| SCHEMBL7459589 | 0.81 | CARM1 (0.40) | PTGER4SCN4APTGER2CARM1PRMT6 | |
| SCHEMBL4987260 | 0.80 | SLC1A3 (0.46) | CARM1PRMT6OPRK1OPRM1OPRD1 | |
| SCHEMBL7996091 | 0.79 | FAAH (0.47) | PTGER4SCN4APTGER2FAAHHSPB1 | |
| SCHEMBL920257 | 0.79 | FAAH (0.47) | PTGER4SCN4APTGER2FAAHHSPB1 | |
| SCHEMBL21776624 | 0.79 | LMNA (0.49) | PARP10MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058550-A4 | SUBSTITUTED SEMICARBAZIDES AND THE USE THEREOF | EURO CELTIQUE SA (LU) | 2002-12-18 | — | — | EP | disclosed |
| US-6281211-B1 | TREATING A DISORDER RESPONSIVE TO THE BLOCKADE OF SODIUM CHANNELS | EURO-CELTIQUE S.A. (LU) | 2001-08-28 | — | — | US | disclosed |
| EP-1058550-A1 | SUBSTITUTED SEMICARBAZIDES AND THE USE THEREOF | Euro-Celtique S.A. (LU) | 2000-12-13 | — | — | EP | disclosed |
| WO-1999039712-A9 | SUBSTITUTED SEMICARBAZIDES AND THE USE THEREOF | COCENSYS INC (US) | 1999-10-21 | — | — | WO | disclosed |
| WO-1999039712-A1 | SUBSTITUTED SEMICARBAZIDES AND THE USE THEREOF | EURO-CELTIQUE S.A. (BE) | 1999-08-12 | — | — | WO | disclosed |