Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 6/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | PNLIP | P16233 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459213 | 0.93 | CARM1 (0.48) | FAAHPTGER4SCN4APTGER2NR3C1 | |
| SCHEMBL4988982 | 0.86 | LIPG (0.45) | FAAHSCN4ACARM1PRMT6PARP10 | |
| SCHEMBL7465300 | 0.84 | CARM1 (0.47) | PTGER4PTGER2CARM1PRMT6SLC6A4 | |
| SCHEMBL7458555 | 0.81 | SLC1A3 (0.44) | CARM1PRMT6SLC6A4 | |
| SCHEMBL7465972 | 0.79 | PTGER4 (0.47) | FAAHPTGER4SCN4APTGER2NR3C1 | |
| SCHEMBL920257 | 0.79 | FAAH (0.47) | FAAHPTGER4SCN4APTGER2NR3C1 | |
| SCHEMBL7464445 | 0.77 | MAPK14 (0.50) | PARP10 | |
| SCHEMBL6142712 | 0.74 | SCN4A (0.45) | SCN4ANR3C1HSPB1PARP10L3MBTL1 | |
| SCHEMBL7455306 | 0.73 | NR3C1 (0.44) | PTGER4SCN4APTGER2NR3C1CARM1 | |
| SCHEMBL7452523 | 0.72 | SMN1; SMN2 (0.46) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281211-B1 | TREATING A DISORDER RESPONSIVE TO THE BLOCKADE OF SODIUM CHANNELS | EURO-CELTIQUE S.A. (LU) | 2001-08-28 | — | — | US | disclosed |
| WO-1999039712-A9 | SUBSTITUTED SEMICARBAZIDES AND THE USE THEREOF | COCENSYS INC (US) | 1999-10-21 | — | — | WO | disclosed |