Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19682467 | 0.83 | TRPV4 (0.49) | MEN1ALDH1A1KMT2AVCAM1SLC22A12 | |
| SCHEMBL8960506 | 0.83 | VCAM1 (0.43) | MEN1ALDH1A1KMT2AVCAM1SLC22A12 | |
| SCHEMBL1263198 | 0.81 | CCR2 (0.45) | MEN1ALDH1A1KMT2AVCAM1SLC22A12 | |
| SCHEMBL8960510 | 0.81 | TRPV4 (0.43) | MEN1ALDH1A1KMT2AVCAM1SLC22A12 | |
| SCHEMBL25176129 | 0.79 | KDM4E (0.46) | MEN1ALDH1A1KMT2ACA1CA2 | |
| SCHEMBL26598944 | 0.78 | CA12 (0.46) | MEN1KMT2ASLC22A12CA1CA2 | |
| SCHEMBL5194623 | 0.76 | CA2 (0.52) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL20451442 | 0.75 | SLC22A12 (0.46) | MEN1ALDH1A1KMT2AVCAM1SLC22A12 | |
| SCHEMBL962913 | 0.74 | CA1 (0.53) | CA1CA2CA12CA9CA3 | |
| SCHEMBL29587590 | 0.74 | CA1 (0.53) | CA1CA2CA12CA9CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |