Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463091 | 0.90 | USP10 (0.50) | EGFRCNR1LMNAHTR6MAPT | |
| SCHEMBL7475684 | 0.89 | EGFR (0.53) | EGFRMETLMNAHTR6MAPT | |
| SCHEMBL7458928 | 0.88 | EGFR (0.47) | EGFRLMNAHTR6MAPTKMT2A | |
| SCHEMBL7466331 | 0.88 | ALDH1A1 (0.48) | EGFRLMNAHTR6MEN1MAPT | |
| SCHEMBL7465445 | 0.88 | HTR6 (0.55) | EGFRCNR1HTR6KMT2A | |
| SCHEMBL7468826 | 0.88 | EGFR (0.56) | EGFRLMNAHTR6MAPTSMN1; SMN2 | |
| SCHEMBL7473662 | 0.87 | USP10 (0.47) | EGFRCNR1LMNAHTR6MAPT | |
| SCHEMBL7465224 | 0.87 | MAPT (0.44) | EGFRMETLMNAHTR6MAPT | |
| SCHEMBL7468699 | 0.87 | PDE5A (0.44) | EGFRLMNAHTR6MAPTKMT2A | |
| SCHEMBL7459198 | 0.86 | MEN1 (0.53) | EGFRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |