Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 11/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469219 | 0.86 | ACHE (0.41) | CYP1A2ALDH1A1HSD17B10MAPTCYP2C19 | |
| SCHEMBL7466525 | 0.82 | MAPT (0.47) | CYP1A2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL7463150 | 0.80 | CYP1A2 (0.41) | CYP1A2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7463135 | 0.79 | CNR1 (0.53) | ALDH1A1KDM4EMAPTCNR1CNR2 | |
| SCHEMBL7469276 | 0.77 | MAPT (0.41) | CYP1A2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7464723 | 0.76 | PDGFRB (0.51) | MAPTPOLB | |
| SCHEMBL7469270 | 0.76 | KMT2A (0.49) | CYP1A2ALDH1A1MAPTCNR1CNR2 | |
| SCHEMBL7468264 | 0.75 | PAK1 (0.48) | POLB | |
| SCHEMBL7458931 | 0.75 | NSD2 (0.56) | ALDH1A1MAPTHTTCNR1CNR2 | |
| SCHEMBL7470513 | 0.74 | CNR1 (0.53) | ALDH1A1MAPTHTTCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |