Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464967 | 0.89 | DNMT1 (0.54) | ALDH1A1KCNH2HRH1DNMT1EHMT2 | |
| SCHEMBL7469300 | 0.84 | KCNH2 (0.49) | ALDH1A1KCNH2HRH1TEAD1TSHR | |
| SCHEMBL645530 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KCNH2TSHRCHRM2CHRM1 | |
| SCHEMBL7472985 | 0.81 | LMNA (0.56) | ALDH1A1KCNH2HRH1TEAD1TSHR | |
| SCHEMBL8792369 | 0.79 | TSHR (0.55) | ALDH1A1KCNH2HRH1TEAD1TSHR | |
| SCHEMBL7469010 | 0.79 | DNMT1 (0.53) | ALDH1A1KCNH2HRH1TSHRDNMT1 | |
| SCHEMBL7470504 | 0.79 | KCNH2 (0.52) | ALDH1A1KCNH2HRH1TSHRDNMT1 | |
| SCHEMBL8190619 | 0.79 | KCNH2 (0.53) | ALDH1A1KCNH2HRH1TEAD1TSHR | |
| SCHEMBL7477007 | 0.79 | KCNH2 (0.62) | ALDH1A1KCNH2HRH1CHRM2CHRM1 | |
| SCHEMBL8948348 | 0.78 | HRH1 (0.52) | ALDH1A1KCNH2HRH1TEAD1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844825-B1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6214845-B1 | AGRICULTURE | FMC CORPORATION | 2001-04-10 | — | — | US | disclosed |
| US-6184234-B1 | EFFECTIVE AGRICULTURAL PESTICIDE FOR TOBACCO, BEETS, BEANS, CABBAGE CROPS | FMC CORPORATION | 2001-02-06 | — | — | US | disclosed |
| EP-0844825-A4 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2000-04-05 | — | — | EP | disclosed |
| US-6030987-A | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines | FMC CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| EP-0844825-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5639763-A | FOR AGRICULTURAL APPLICATIONS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| WO-1996036228-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1996-11-21 | — | — | WO | disclosed |