Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478830 | 0.88 | RAB9A (0.67) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL14825155 | 0.76 | RAB9A (0.75) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8146339 | 0.76 | ALDH1A1 (0.51) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL126387 | 0.75 | KMT2A (0.66) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL10087445 | 0.70 | LTA4H (0.60) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7125440 | 0.69 | SREBF2 (0.58) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7465015 | 0.68 | RAB9A (0.56) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL18114095 | 0.68 | MEN1 (0.74) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL172198 | 0.66 | LTA4H (0.54) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11887625 | 0.66 | RAB9A (0.60) | RAB9AALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-B1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMA (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6458959-B1 | VIRICIDES AND ENZYME INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-10-01 | — | — | US | disclosed |
| US-6348477-B1 | SUBSTITUTED PHENYL THIAZOLE DERIVATIVES AS VIRICIDES | BOEHRINGER INGELHEIM(CANADA) LTD. (CA) | 2002-02-19 | — | — | US | disclosed |
| US-6288091-B1 | COMPOUNDS SUCH AS 2,2,2-TRICHLOROETHYL N-(4-(2-AMINO-4-THIAZOLYL)-PHENYL)CARBAMATE THAT INHIBIT THE HERPES HELCASE-PRIMASE ENZYME COMPLEX | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-11 | — | — | US | disclosed |
| US-6057451-A | AMINOTHIAZOLE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |