Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 7/20 | 0.43 |
| ▸ | HRH2 | P25021 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148260 | 0.85 | ROCK2 (0.51) | RAB9AMEN1KMT2APOLBMAPT | |
| SCHEMBL7478830 | 0.82 | RAB9A (0.67) | ALDH1A1RAB9AMEN1KMT2APOLB | |
| SCHEMBL4876699 | 0.80 | LTA4H (0.52) | ALDH1A1RAB9AMEN1KMT2APOLB | |
| SCHEMBL10087445 | 0.79 | LTA4H (0.60) | ALDH1A1RAB9AMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL4870688 | 0.79 | AOC3 (0.52) | ALDH1A1RAB9AMEN1KMT2APOLB | |
| SCHEMBL4582523 | 0.79 | ALDH1A1 (0.56) | ALDH1A1RAB9AMEN1KMT2APOLB | |
| SCHEMBL7467074 | 0.76 | RAB9A (0.65) | ALDH1A1RAB9AMEN1KMT2APOLB | |
| SCHEMBL8152325 | 0.75 | LTA4H (0.52) | ALDH1A1RAB9AMEN1KMT2APOLB | |
| SCHEMBL31298054 | 0.74 | HPGD (0.52) | RAB9AMEN1KMT2APOLBGAA | |
| SCHEMBL3129405 | 0.74 | LTA4H (0.64) | ALDH1A1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057451-A | AMINOTHIAZOLE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |