Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207588 | 0.87 | SLC6A9 (0.32) | — | |
| SCHEMBL8444961 | 0.80 | KDM4E (0.30) | KDM4ESMN1; SMN2 | |
| SCHEMBL7211962 | 0.71 | HPGD (0.33) | — | |
| SCHEMBL7207584 | 0.71 | DRD2 (0.47) | SMN1; SMN2 | |
| SCHEMBL7467290 | 0.71 | — | — | |
| SCHEMBL7207522 | 0.70 | MEN1 (0.31) | — | |
| SCHEMBL7483872 | 0.69 | SLC6A9 (0.40) | KDM4ESMN1; SMN2 | |
| SCHEMBL7482639 | 0.66 | KMT2A (0.42) | KDM4E | |
| SCHEMBL27459264 | 0.65 | ALDH1A1 (0.37) | KDM4E | |
| SCHEMBL84280 | 0.64 | ALDH1A1 (0.41) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923576-B1 | 4-AMINOETHOXY-INDOLONE DERIVATIVES AS DOPAMINE D2 AGONISTS | WYETH CORP (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-0923576-A1 | 4-AMINOETHOXY-INDOLONE DERIVATIVES AS DOPAMINE D2 AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5760070-A | TREATMENT OF PSYCHOLOGICAL DISORDERS, TOURETTE'S SYNDROME, ALCOHOL OR DRUG ADDICTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |
| WO-1998008843-A1 | 4-AMINOETHOXY-INDOLONE DERIVATIVES AS DOPAMINE D2 AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-05 | — | — | WO | disclosed |