Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | HTT | P42858 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | CLK3 | P49761 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475194 | 0.82 | EGFR (0.66) | SMN1; SMN2HTTLMNAMAPK1HPGD | |
| SCHEMBL7472222 | 0.81 | NPC1 (0.62) | LMNAMAPK1HPGDTSHRALDH1A1 | |
| SCHEMBL7473179 | 0.80 | MAPK1 (0.58) | HTTLMNAMAPK1EGFRMAPT | |
| SCHEMBL7468278 | 0.80 | ALDH1A1 (0.56) | SMN1; SMN2HTTLMNAMAPK1HPGD | |
| SCHEMBL7464189 | 0.80 | MAPT (0.56) | SMN1; SMN2HTTLMNAMAPK1HPGD | |
| SCHEMBL7470683 | 0.80 | KDM4E (0.61) | LMNAMAPK1HPGDALDH1A1RAB9A | |
| SCHEMBL7472725 | 0.79 | EGFR (0.61) | HTTMAPK1EGFRAURKARPS6KB1 | |
| SCHEMBL7465660 | 0.79 | EGFR (0.56) | SMN1; SMN2MAPK1ALDH1A1EGFRKDM4E | |
| SCHEMBL7474842 | 0.79 | RXFP1 (0.62) | SMN1; SMN2HTTLMNAMAPK1HPGD | |
| SCHEMBL7560008 | 0.79 | MAPK1 (0.50) | SMN1; SMN2HTTLMNAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |