Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | CLK3 | P49761 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468278 | 0.89 | ALDH1A1 (0.56) | MAPTHTR6MAPK1SMN1; SMN2LMNA | |
| SCHEMBL7475565 | 0.86 | ALDH1A1 (0.53) | MAPTHTR6MAPK1SMN1; SMN2LMNA | |
| SCHEMBL7469571 | 0.85 | EGFR (0.56) | MAPTHRH4SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7459991 | 0.85 | LMNA (0.52) | MAPTMAPK1HRH4LMNAALDH1A1 | |
| SCHEMBL7473166 | 0.82 | HTR6 (0.55) | MAPTHTR6HRH4SMN1; SMN2LMNA | |
| SCHEMBL7470773 | 0.80 | PDE5A (0.59) | SMN1; SMN2ALDH1A1CLK4 | |
| SCHEMBL7465055 | 0.80 | HTR6 (0.55) | MAPTHTR6MAPK1HRH4SMN1; SMN2 | |
| SCHEMBL7467287 | 0.80 | SMN1; SMN2 (0.62) | MAPTMAPK1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7476281 | 0.80 | HRH4 (0.51) | MAPTHTR6MAPK1HRH4SMN1; SMN2 | |
| SCHEMBL7474097 | 0.77 | HRH4 (0.56) | HTR6HRH4HTTEIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |