Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 15/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 15/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467434 | 0.88 | ITGB1 (0.50) | ITGB1ITGA4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7468077 | 0.86 | DGAT1 (0.45) | ITGB1ITGA4DGAT1MEN1KMT2A | |
| SCHEMBL7467182 | 0.86 | DGAT1 (0.45) | ITGB1ITGA4DGAT1MEN1KMT2A | |
| SCHEMBL7468112 | 0.80 | ITGB3 (0.50) | ITGB1ITGA4RAB9ASMN1; SMN2ITGB7 | |
| SCHEMBL7467201 | 0.76 | ITGB1 (0.51) | ITGB1ITGA4SMN1; SMN2ITGB7 | |
| SCHEMBL7687421 | 0.76 | ITGB1 (0.51) | ITGB1ITGA4SMN1; SMN2ITGB7 | |
| SCHEMBL7467289 | 0.76 | RAB9A (0.51) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7466878 | 0.76 | ATM (0.43) | ITGB1ITGA4DGAT1MEN1KMT2A | |
| SCHEMBL7467449 | 0.76 | ATM (0.43) | ITGB1ITGA4DGAT1MEN1KMT2A | |
| SCHEMBL7423736 | 0.74 | ITGB1 (0.58) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |