Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 17/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751563 | 0.89 | TYMP (0.38) | LMNAADORA3 | |
| SCHEMBL748569 | 0.85 | HINT1 (0.40) | NT5EADORA3 | |
| SCHEMBL8915086 | 0.78 | LMNA (0.38) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL749811 | 0.71 | RNASE1 (0.38) | LMNAALDH1A1 | |
| SCHEMBL19987187 | 0.70 | LMNA (0.44) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL7658873 | 0.69 | LMNA (0.42) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL748797 | 0.69 | HIF1A (0.31) | LMNAMAPT | |
| SCHEMBL5313453 | 0.68 | TYMP (0.40) | LMNAADORA3 | |
| SCHEMBL9893826 | 0.68 | LMNA (0.44) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL21511189 | 0.68 | LMNA (0.46) | LMNATP53ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430034-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | Southern Research Institute (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132513-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (US) | 2010-11-18 | — | — | WO | disclosed |