Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.33 |
| ▸ | GNMT | Q14749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746752 | 0.89 | LMNA (0.38) | LMNAADORA3 | |
| SCHEMBL748569 | 0.82 | HINT1 (0.40) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL5313453 | 0.79 | TYMP (0.40) | TYMPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL749811 | 0.72 | RNASE1 (0.38) | TYMPLMNA | |
| SCHEMBL8620535 | 0.71 | TYMP (0.42) | TYMPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6424553 | 0.70 | P2RX7 (0.34) | TYMPP2RX7 | |
| SCHEMBL748797 | 0.69 | HIF1A (0.31) | LMNA | |
| SCHEMBL9893618 | 0.67 | LMNA (0.45) | TYMPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8915086 | 0.67 | LMNA (0.38) | LMNAADORA3ADORA2A | |
| SCHEMBL6384023 | 0.67 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430034-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | Southern Research Institute (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132513-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (US) | 2010-11-18 | — | — | WO | disclosed |