SCHEMBL7467685

SCHEMBL7467685

CCOC(=O)OC1SCC(C)C1=O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
SOAT1 P35610 1/20 0.35
GLA P06280 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP14 P50281 1/20 0.34
LMNA P02545 2/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7476315 0.83 ALDH1A1 (0.36) ALDH1A1SOAT1GLAMMP2MMP9
SCHEMBL7467051 0.83 ALDH1A1 (0.36) ALDH1A1SOAT1GLAMMP2MMP9
SCHEMBL7469088 0.81 CYP1A2 (0.33)
SCHEMBL7473040 0.80 GLA (0.35) ALDH1A1SOAT1GLAMMP2MMP9
SCHEMBL7467164 0.79 ALDH1A1 (0.33) ALDH1A1SOAT1MMP2MMP9MMP8
SCHEMBL7034548 0.73 KDM4E (0.38) ALDH1A1MEN1HPGDKMT2AHSD17B10
SCHEMBL9698419 0.70 CYP2D6 (0.40) ALDH1A1SOAT1GLAMMP2MMP9
SCHEMBL7464039 0.70 MMP2 (0.34) ALDH1A1SOAT1GLAMMP2MMP9
SCHEMBL7470776 0.70 MMP2 (0.34) ALDH1A1SOAT1GLAMMP2MMP9
SCHEMBL6612598 0.68 ALDH1A1 (0.34) ALDH1A1SOAT1MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed
WO-1997016449-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-09 WO disclosed