SCHEMBL7476315

SCHEMBL7476315

CCOC(=O)OC1SCC(CC)C1=O

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
MMP8 P22894 2/20 0.36
MMP14 P50281 2/20 0.36
SOAT1 P35610 1/20 0.34
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7470544 0.86 MMP2 (0.33) MMP2MMP9MMP14
SCHEMBL7467685 0.83 ALDH1A1 (0.38) ALDH1A1MMP2MMP9MMP8MMP14
SCHEMBL7467616 0.82 MMP2 (0.36) MMP2MMP9MMP14
SCHEMBL7467051 0.81 ALDH1A1 (0.36) ALDH1A1MMP2MMP9MMP8MMP14
SCHEMBL7464039 0.81 MMP2 (0.34) ALDH1A1MMP2MMP9MMP8MMP14
SCHEMBL7467164 0.78 ALDH1A1 (0.33) ALDH1A1MMP2MMP9MMP8MMP14
SCHEMBL7030761 0.74 KDM4E (0.38) ALDH1A1MMP2MMP9MMP8MMP14
SCHEMBL7473040 0.70 GLA (0.35) ALDH1A1MMP2MMP9MMP8MMP14
SCHEMBL9698419 0.69 CYP2D6 (0.40) ALDH1A1MMP2MMP9MMP8MMP14
SCHEMBL7470776 0.69 MMP2 (0.34) ALDH1A1MMP2MMP9MMP8MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed
WO-1997016449-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-09 WO disclosed