SCHEMBL7473040

SCHEMBL7473040

CCOC(=O)OC1SCC(C)C1=NO

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.35
ALDH1A1 P00352 1/20 0.34
SOAT1 P35610 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP14 P50281 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7470776 0.84 MMP2 (0.34) GLAALDH1A1SOAT1MMP2MMP9
SCHEMBL7464039 0.84 MMP2 (0.34) GLAALDH1A1SOAT1MMP2MMP9
SCHEMBL7466215 0.81 ALDH1A1 (0.31) ALDH1A1MMP2MMP9MMP8MMP14
SCHEMBL7467685 0.80 ALDH1A1 (0.38) GLAALDH1A1SOAT1MMP2MMP9
SCHEMBL7030188 0.76 KDM4E (0.33) GLAALDH1A1
SCHEMBL7469762 0.71 MMP2 (0.31) MMP2MMP9MMP14
SCHEMBL6611472 0.70 ALDH1A1 (0.32) GLAALDH1A1SOAT1MMP2MMP9
SCHEMBL7476315 0.70 ALDH1A1 (0.36) GLAALDH1A1SOAT1MMP2MMP9
SCHEMBL7467051 0.70 ALDH1A1 (0.36) GLAALDH1A1SOAT1MMP2MMP9
SCHEMBL7033442 0.68 PPM1B (0.33) MMP2MMP9MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed
WO-1997016449-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-09 WO disclosed