Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 10/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475093 | 0.87 | PDE5A (0.68) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7468081 | 0.85 | KMT2A (0.42) | PDE5AEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL7474799 | 0.81 | PDE5A (0.59) | PDE5AEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL7461202 | 0.80 | PDE5A (0.53) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7465102 | 0.80 | PDE5A (0.54) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7467801 | 0.79 | EGFR (0.63) | PDE5AEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL7465660 | 0.78 | EGFR (0.56) | EGFRMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7474842 | 0.78 | RXFP1 (0.62) | EGFRALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL7469892 | 0.77 | EGFR (0.55) | EGFRALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7475194 | 0.77 | EGFR (0.66) | EGFRSMN1; SMN2LMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |