Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 15/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474799 | 0.94 | PDE5A (0.59) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7461202 | 0.89 | PDE5A (0.53) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7474841 | 0.87 | PDE5A (0.48) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7473179 | 0.83 | MAPK1 (0.58) | — | |
| SCHEMBL7467801 | 0.83 | EGFR (0.63) | PDE5AMEN1KMT2AALDH1A1 | |
| SCHEMBL9921503 | 0.83 | PDE5A (0.69) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7465102 | 0.83 | PDE5A (0.54) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7472725 | 0.82 | EGFR (0.61) | — | |
| SCHEMBL7470773 | 0.82 | PDE5A (0.59) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7473397 | 0.82 | PDE5A (0.59) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |