Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 8/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3314580 | 0.89 | DPP4 (0.53) | DPP4DPP7TACR1HTR2AHTR2C | |
| SCHEMBL7749807 | 0.85 | RIPK1 (0.46) | DPP4DPP7TAAR1HTR2AHTR2C | |
| SCHEMBL7464685 | 0.82 | USP19 (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL25913721 | 0.81 | DPP4 (0.47) | DPP4DPP7TACR1 | |
| SCHEMBL3697218 | 0.81 | DPP4 (0.47) | DPP4DPP7TACR1 | |
| SCHEMBL5419310 | 0.80 | DPP4 (0.46) | DPP4DPP7TACR1CCNCCDK8 | |
| SCHEMBL5480616 | 0.80 | DPP4 (0.46) | DPP4DPP7TACR1CCNCCDK8 | |
| SCHEMBL16644644 | 0.79 | SLC6A9 (0.60) | — | |
| SCHEMBL19305170 | 0.77 | DPP4 (0.43) | DPP4DPP7TACR1CCNCCDK8 | |
| SCHEMBL5411381 | 0.77 | DPP4 (0.43) | DPP4DPP7TACR1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103313982-A | Phenyl-isoxazole derivatives and process for the preparation thereof | IL YANG PHARM CO LTD | 2013-09-18 | — | — | CN | claimed |
| CN-103313982-A | Phenyl-isoxazole derivatives and process for the preparation thereof | IL YANG PHARM CO LTD | 2013-09-18 | — | — | CN | disclosed |
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |