Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP19 | O94966 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14833502 | 0.90 | MMP1 (0.44) | MAOAMMP1MMP3MMP7MMP9 | |
| SCHEMBL12520600 | 0.85 | GAA (0.48) | USP19MAOAMMP1MMP3MMP7 | |
| SCHEMBL7467909 | 0.82 | DPP4 (0.54) | HTR2AHTR2CHTR2B | |
| SCHEMBL7749807 | 0.80 | RIPK1 (0.46) | USP19SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL778839 | 0.80 | FPR1 (0.55) | SMN1; SMN2CHRNA7KCNH2 | |
| SCHEMBL659344 | 0.79 | MAOA (0.49) | MAOAMMP1MMP3MMP7MMP9 | |
| SCHEMBL19066025 | 0.77 | MAOA (0.44) | MAOAMMP1MMP3MMP7MMP9 | |
| Hydrochloric Acid SCHEMBL22217670 | 0.76 | HRH3 (0.46) | MAOATSHRSMN1; SMN2CHRNA7KCNH2 | |
| Hydrochloric Acid SCHEMBL20236464 | 0.76 | HRH3 (0.46) | MAOATSHRSMN1; SMN2KCNH2 | |
| SCHEMBL14833501 | 0.75 | MAOA (0.43) | MAOAMMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |