Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 7/20 | 0.63 |
| ▸ | KDR | P35968 | 7/20 | 0.63 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.59 |
| ▸ | MET | P08581 | 2/20 | 0.58 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | LYN | P07948 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | HCK | P08631 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901281 | 0.83 | PDGFRA (0.68) | PDGFRAKDRPDGFRBMETFGFR2 | |
| SCHEMBL4471141 | 0.82 | FGFR2 (0.83) | PDGFRAKDRPDGFRBMETFGFR2 | |
| SCHEMBL5825496 | 0.82 | PDGFRA (0.67) | PDGFRAKDRPDGFRBMETFGFR2 | |
| SCHEMBL7487173 | 0.80 | FGFR2 (0.76) | PDGFRAKDRPDGFRBMETFGFR2 | |
| SCHEMBL7486400 | 0.79 | FGFR2 (0.84) | PDGFRAKDRPDGFRBFGFR2EGFR | |
| SCHEMBL7456971 | 0.78 | NR4A2 (0.51) | PDGFRAKDRPDGFRBMETAURKA | |
| Fluorobenzene SCHEMBL28724473 | 0.78 | FGFR2 (0.65) | PDGFRAKDRPDGFRBMETFGFR2 | |
| SCHEMBL7479859 | 0.77 | PDGFRA (1.00) | PDGFRAKDRMETAURKARIPK2 | |
| SCHEMBL7489927 | 0.77 | PDGFRA (1.00) | PDGFRAKDRMETFGFR2AURKA | |
| SCHEMBL7460943 | 0.77 | PDGFRA (0.56) | PDGFRAKDRPDGFRBMETFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |