SCHEMBL7467948

SCHEMBL7467948

Cc1cnc(-c2ccc(C(F)(F)F)s2)nc1Oc1ccnc(OC(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPP1CA P62136 1/20 0.33
KMT2A Q03164 1/20 0.33
DRD1 P21728 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7470124 0.85 PPP1CA (0.35) PPP1CAKMT2ADRD1
SCHEMBL8126004 0.82 TRPV3 (0.31) DRD1
SCHEMBL7465821 0.80 GAA (0.35)
SCHEMBL8126005 0.73 BLM (0.31)
SCHEMBL7467157 0.71 KMT2A (0.46) KMT2A
SCHEMBL5211817 0.67 NPSR1 (0.38) KMT2A
SCHEMBL8478571 0.66 F2RL3 (0.39) KMT2ADRD1
SCHEMBL8126833 0.65 ALOX5AP (0.34)
SCHEMBL8118893 0.65 RAB9A (0.33)
SCHEMBL8720836 0.65 KMT2A (0.36) PPP1CAKMT2ADRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0819690-B1 Herbicidal 6-thienyl and 4-thienyl pyrimidines BASF AG (DE) 2002-10-09 EP claimed
US-5922726-A Herbicidal 6-thienyl pyridines and 4-thienyl pyrimidines AMERICAN CYANAMID COMPANY (US) 1999-07-13 US claimed
EP-0819690-A2 Herbicidal 6-thienyl and 4-thienyl pyrimidines American Cyanamid Company (US) 1998-01-21 EP claimed