Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467948 | 0.85 | PPP1CA (0.33) | PPP1CAKMT2ADRD1 | |
| SCHEMBL8126833 | 0.80 | ALOX5AP (0.34) | ALOX5APFEN1TGFBR1PDE10AGRIN2B | |
| SCHEMBL7467157 | 0.79 | KMT2A (0.46) | KMT2ATGFBR1GRIN1GRIN2BALDH1A1 | |
| SCHEMBL5211817 | 0.70 | NPSR1 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL8720836 | 0.70 | KMT2A (0.36) | PPP1CAKMT2ADRD1ALDH1A1CYP1A2 | |
| SCHEMBL8126836 | 0.70 | BLM (0.38) | ALOX5APFEN1TGFBR1AAK1CYP1A2 | |
| SCHEMBL5553199 | 0.70 | ALDH1A1 (0.35) | PPP1CAKMT2AALOX5APFEN1DRD1 | |
| SCHEMBL8118893 | 0.68 | RAB9A (0.33) | — | |
| SCHEMBL27894825 | 0.68 | LOXL2 (0.50) | ALOX5APFEN1TGFBR1CYP2C19IDO1 | |
| SCHEMBL7011308 | 0.67 | S1PR1 (0.47) | PPP1CAKMT2AALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819690-B1 | Herbicidal 6-thienyl and 4-thienyl pyrimidines | BASF AG (DE) | 2002-10-09 | — | — | EP | claimed |
| US-5922726-A | Herbicidal 6-thienyl pyridines and 4-thienyl pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-07-13 | — | — | US | claimed |
| EP-0819690-A2 | Herbicidal 6-thienyl and 4-thienyl pyrimidines | American Cyanamid Company (US) | 1998-01-21 | — | — | EP | claimed |