Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 5/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468566 | 0.76 | RAB9A (0.55) | ALDH1A1SMN1; SMN2LMNAHPGDMAPT | |
| SCHEMBL7473221 | 0.75 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2LMNAHPGDMAPT | |
| SCHEMBL22413647 | 0.74 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2LMNAHPGDFAAH | |
| SCHEMBL5240163 | 0.73 | GABRA5 (0.50) | ALDH1A1SMN1; SMN2LMNAHPGDMAPT | |
| SCHEMBL2749781 | 0.72 | CNR1 (0.48) | ALDH1A1SMN1; SMN2LMNAHPGDFAAH | |
| SCHEMBL7467047 | 0.69 | RAB9A (0.52) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL15553657 | 0.69 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2LMNAHPGDFAAH | |
| SCHEMBL10520818 | 0.69 | HPGD (0.48) | ALDH1A1SMN1; SMN2LMNAHPGDMAPT | |
| SCHEMBL15269495 | 0.69 | FAAH (0.54) | ALDH1A1SMN1; SMN2LMNAFAAHACHE | |
| SCHEMBL366845 | 0.68 | RAB9A (0.54) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-B1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMA (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6057451-A | AMINOTHIAZOLE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |