Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31169750 | 0.98 | CHRM2 (0.65) | CHRM2CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL6625017 | 0.89 | CHRM2 (0.73) | CHRM2CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL1642902 | 0.87 | CHRM2 (0.77) | CHRM2CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL10338545 | 0.87 | CHRM2 (0.77) | CHRM2CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL29256190 | 0.85 | CHRM2 (0.80) | CHRM2CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL29256194 | 0.85 | CHRM2 (0.80) | CHRM2CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL30924842 | 0.85 | CHRM2 (0.80) | CHRM2CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL11191131 | 0.85 | CHRM2 (0.80) | CHRM2CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL30924843 | 0.85 | CHRM2 (0.80) | CHRM2CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL16295729 | 0.85 | CHRM2 (0.80) | CHRM2CYP1A2CYP2D6TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872911-B2 | Alpha-aminoamidine polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-01-23 | — | — | US | disclosed |
| US-20160137785-A1 | POLY(BETA-AMINO ALCOHOLS), THEIR PREPARATION, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-05-19 | — | — | US | disclosed |
| US-9193827-B2 | Poly(beta-amino alcohols), their preparation, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-11-24 | — | — | US | disclosed |
| US-20140322309-A1 | ALPHA-AMINOAMIDINE POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLO (US) | 2014-10-30 | — | — | US | disclosed |
| US-20130302401-A1 | POLY(BETA-AMINO ALCOHOLS), THEIR PREPARATION, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-11-14 | — | — | US | disclosed |
| US-8349839-B2 | Inhibitors of HIV replication | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-08 | — | — | US | disclosed |
| US-8349839-B2 | Inhibitors of HIV replication | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-08 | — | — | US | disclosed |
| WO-2010115264-A1 | INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-14 | — | — | WO | disclosed |
| US-20100261714-A1 | INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-14 | — | — | US | disclosed |
| US-20100261714-A1 | INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-14 | — | — | US | disclosed |
| EP-0873331-B1 | BENZOFURAN CARBOXAMIDES AND SULPHONAMIDES | DARWIN DISCOVERY LTD (GB) | 2002-04-03 | — | — | EP | disclosed |
| US-5773467-A | Benzofuran sulphonanmides | CHIROSCIENCE, LTD. (GB) | 1998-06-30 | — | — | US | disclosed |
| US-4404018-A | Furfuryl amides of phenoxyphenoxyalkanoic acids and herbicidal use | VELSICOL CHEMICAL CORPORATION (US) | 1983-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322309-A1 | ALPHA-AMINOAMIDINE POLYMERS AND USES THEREOF | AAAS, AADAT, INMT | CHRM2 2082/4885CYP1A2 3841/4885CYP2D6 3765/4885 |
| US-20160137785-A1 | POLY(BETA-AMINO ALCOHOLS), THEIR PREPARATION, AND USES THEREOF | PDGFA, MIF, FIBP | CHRM2 1806/4885CYP1A2 4142/4885CYP2D6 4616/4885 |
| US-20100261714-A1 | INHIBITORS OF HIV REPLICATION | RTF2, POLR1A, REV1 | CHRM2 4134/4885CYP1A2 577/4885CYP2D6 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.