Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.54 |
| ▸ | TEK | Q02763 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460710 | 0.89 | RHEB (0.51) | KDREGFRAPPPDGFRASMN1; SMN2 | |
| SCHEMBL7461823 | 0.87 | APP (0.58) | KDRAPPPDGFRBPDGFRASMN1; SMN2 | |
| SCHEMBL7457252 | 0.86 | L3MBTL1 (0.55) | KDREGFRAPPPDGFRBPDGFRA | |
| SCHEMBL7463576 | 0.84 | APP (0.52) | KDRAPPPDGFRBPDGFRASMN1; SMN2 | |
| SCHEMBL7463496 | 0.84 | EGFR (0.64) | KDREGFRAPPSMN1; SMN2LMNA | |
| SCHEMBL7467633 | 0.84 | ALK (0.50) | KDREGFRAPPPDGFRASMN1; SMN2 | |
| SCHEMBL7461569 | 0.84 | LMNA (0.49) | KDREGFRAURKAMETTEK | |
| SCHEMBL7463120 | 0.83 | FGFR2 (0.48) | KDREGFRAPPSMN1; SMN2LMNA | |
| SCHEMBL7454814 | 0.83 | EGFR (0.56) | KDREGFRAURKAMETTEK | |
| SCHEMBL1702115 | 0.82 | LMNA (0.61) | SMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |