Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463576 | 0.89 | APP (0.52) | LMNASMN1; SMN2NR4A2SOS2KDR | |
| SCHEMBL7467633 | 0.89 | ALK (0.50) | LMNASMN1; SMN2EGFRNR4A2SOS2 | |
| SCHEMBL7468546 | 0.89 | KDR (0.56) | LMNASMN1; SMN2EGFRKDRMAPK1 | |
| SCHEMBL7461569 | 0.89 | LMNA (0.49) | LMNASMN1; SMN2EGFRNR4A2SOS2 | |
| SCHEMBL7457252 | 0.89 | L3MBTL1 (0.55) | LMNASMN1; SMN2EGFRNR4A2SOS2 | |
| SCHEMBL7463496 | 0.89 | EGFR (0.64) | LMNASMN1; SMN2EGFRNR4A2SOS2 | |
| SCHEMBL27665771 | 0.88 | KDR (0.52) | RHEBSMN1; SMN2EGFRLCKKDR | |
| SCHEMBL7465060 | 0.87 | APP (0.50) | LMNASMN1; SMN2NR4A2SOS2KDR | |
| SCHEMBL7462623 | 0.86 | LMNA (0.54) | LMNASMN1; SMN2NR4A2SOS2KDR | |
| SCHEMBL7529202 | 0.85 | NR4A2 (0.59) | LMNASMN1; SMN2NR4A2SOS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5240940-A | Synergistic nmixture | DOWELANCO (US) | 1993-08-31 | — | — | US | disclosed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | disclosed |