SCHEMBL7468645

SCHEMBL7468645

CCCOC(=O)c1cccc(OC(F)F)c1.O=S(=O)(O)Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.52
LMNA P02545 3/20 0.51
KDM4E B2RXH2 1/20 0.50
MAPK1 P28482 1/20 0.46
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 1/20 0.45
ADRB2 P07550 1/20 0.45
ADRB1 P08588 1/20 0.45
ADRB3 P13945 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
STS P08842 1/20 0.44
NPSR1 Q6W5P4 2/20 0.43
MAPT P10636 2/20 0.43
RAB9A P51151 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
ELANE P08246 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7464613 0.90 LMNA (0.53) TDP1LMNAKDM4EMAPK1KMT2A
SCHEMBL7468451 0.88 ALDH1A1 (0.51) LMNAKMT2AMEN1SMN1; SMN2ALDH1A1
SCHEMBL7464641 0.86 KMT2A (0.61) LMNAKDM4EKMT2AMEN1SMN1; SMN2
SCHEMBL27516867 0.84 ALDH1A1 (0.52) TDP1LMNAKMT2AMEN1SMN1; SMN2
SCHEMBL7466621 0.83 KMT2A (0.51) TDP1LMNAKDM4EKMT2AMEN1
SCHEMBL7471305 0.82 LMNA (0.54) TDP1LMNAKDM4ESMN1; SMN2ALDH1A1
SCHEMBL7471813 0.81 LMNA (0.57) TDP1LMNAKDM4EALDH1A1L3MBTL1
SCHEMBL7471955 0.81 RAB9A (0.49) TDP1LMNAKDM4EKMT2AMEN1
SCHEMBL7530948 0.80 LMNA (0.55) TDP1LMNAKDM4EALDH1A1ADRB2
SCHEMBL7465769 0.80 LMNA (0.59) TDP1LMNAKDM4EMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed