Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470706 | 0.81 | P2RX3 (0.39) | — | |
| SCHEMBL7472788 | 0.80 | RORC (0.42) | ALDH1A1MEN1KMT2ARORCNPSR1 | |
| SCHEMBL7476563 | 0.80 | LMNA (0.36) | HPGDCMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL7468861 | 0.79 | PPARG (0.35) | HPGDCMA1MEN1KMT2A | |
| SCHEMBL8820570 | 0.78 | MEN1 (0.35) | HPGDCMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL7472616 | 0.77 | P2RX3 (0.34) | CMA1ALDH1A1KDM4E | |
| SCHEMBL7476618 | 0.77 | ACLY (0.37) | HPGDCMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL8819833 | 0.76 | KMT2A (0.36) | HPGDALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL8818687 | 0.76 | HPGD (0.39) | HPGDALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL7471410 | 0.75 | PPARG (0.33) | HPGDCMA1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891336-B1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AG (DE) | 2002-06-05 | — | — | EP | disclosed |
| EP-0891336-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |