Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 7/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGAV | P06756 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382763 | 0.88 | ITGB3 (0.48) | ITGB3ITGAVITGA2BSFRP1DRD2 | |
| SCHEMBL7457979 | 0.87 | SFRP1 (0.42) | KAT6AITGB3ITGAVITGA2BALDH1A1 | |
| SCHEMBL7470713 | 0.87 | KAT6A (0.39) | KAT6AITGB3ITGAVITGA2BSFRP1 | |
| SCHEMBL7469287 | 0.87 | ITGB3 (0.45) | ITGB3ITGAVITGA2BEPHX2 | |
| SCHEMBL383238 | 0.85 | ITGB3 (0.52) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL6501603 | 0.85 | RORC (0.37) | KAT6AITGB3ITGAVITGA2BALDH1A1 | |
| SCHEMBL7464227 | 0.85 | ITGB3 (0.37) | ITGB3ITGAVITGA2BLMNADRD2 | |
| SCHEMBL382204 | 0.85 | ITGB3 (0.39) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL7053630 | 0.85 | ITGB3 (0.55) | ITGB3ITGAVITGA2BALDH1A1SMN1; SMN2 | |
| SCHEMBL7469399 | 0.85 | SFRP1 (0.40) | ITGB3ITGAVITGA2BSFRP1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | disclosed |