Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.37 |
| ▸ | ITGAV | P06756 | 5/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382204 | 0.94 | ITGB3 (0.39) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL381746 | 0.88 | ITGB3 (0.41) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL7469287 | 0.86 | ITGB3 (0.45) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL383238 | 0.86 | ITGB3 (0.52) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL7469099 | 0.85 | KAT6A (0.41) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL7468383 | 0.85 | ITGB3 (0.41) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL6507434 | 0.84 | DRD2 (0.34) | ITGB3ITGAVITGA2BKDM4EDRD2 | |
| SCHEMBL382763 | 0.84 | ITGB3 (0.48) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL381838 | 0.83 | ITGB3 (0.51) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL7457979 | 0.83 | SFRP1 (0.42) | ITGB3ITGAVITGA2BKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | claimed |
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | disclosed |