Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA6 | P23280 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457655 | 0.91 | CA1 (0.51) | ALDH1A1KDM4EMAPTPOLBCA1 | |
| SCHEMBL12408515 | 0.89 | KDM4E (0.49) | ALDH1A1KDM4EMAPTPOLBCA1 | |
| SCHEMBL9947508 | 0.88 | PLA2G2A (0.49) | ALDH1A1KDM4EMAPTPOLBCA1 | |
| SCHEMBL7964491 | 0.86 | KDM4E (0.60) | ALDH1A1KDM4EMAPTPOLBCA1 | |
| SCHEMBL7463651 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTPOLBCA1 | |
| SCHEMBL10660422 | 0.80 | CA9 (0.47) | ALDH1A1KDM4EMAPTCA1CA9 | |
| SCHEMBL8677199 | 0.78 | KDM4E (0.47) | ALDH1A1KDM4EMAPTPOLBCA1 | |
| SCHEMBL7461497 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTPOLBCA1 | |
| SCHEMBL11856166 | 0.75 | KDM4E (0.55) | ALDH1A1KDM4EMAPTPOLBCA1 | |
| SCHEMBL1263805 | 0.74 | CA1 (0.54) | ALDH1A1KDM4EMAPTPOLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032572-B1 | PYRANONES, METHOD FOR THE PRODUCTION AND USE THEREOF | SCHWABE WILLMAR GMBH & CO (DE) | 2002-12-11 | — | — | EP | disclosed |