Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | PTPRB | P23467 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | AGER | Q15109 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964491 | 0.80 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8677199 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL7469324 | 0.75 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL28645298 | 0.74 | ALOX15 (0.65) | ALDH1A1HPGDHSD17B10PTPRBMAPT | |
| SCHEMBL7457655 | 0.74 | CA1 (0.51) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL7461497 | 0.74 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL7463651 | 0.74 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL5387851 | 0.74 | LMNA (0.56) | HPGDHSD17B10PTPRBPOLBMCL1 | |
| SCHEMBL1613109 | 0.74 | HPGD (0.56) | ALDH1A1HPGDHSD17B10PTPRBMAPT | |
| SCHEMBL9901826 | 0.73 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969323-A | Photo-crosslinkable 2-pyrone polymers and processes for the manufacture thereof | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-07-13 | — | — | US | disclosed |