Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466276 | 0.92 | MAPK1 (0.56) | ACHEBACE1MAPK1ABCG2NPSR1 | |
| SCHEMBL7468426 | 0.87 | WDR5 (0.42) | MAPK1HTR6NPSR1POLBMAPT | |
| SCHEMBL7474960 | 0.87 | MAPT (0.43) | MAPK1HTR6NPSR1POLBMAPT | |
| SCHEMBL7469504 | 0.87 | SMN1; SMN2 (0.59) | ACHEBACE1MAPK1ABCG2POLB | |
| SCHEMBL7466158 | 0.85 | HTR6 (0.55) | MAPK1HTR6NPSR1MAPTEGFR | |
| SCHEMBL7471138 | 0.85 | MAPT (0.45) | MAPK1HTR6POLBMAPTPIK3CA | |
| SCHEMBL7467721 | 0.85 | MEN1 (0.45) | ACHEBACE1MAPK1HTR6MAPT | |
| SCHEMBL7467406 | 0.83 | MAPT (0.44) | MAPK1HTR6NPSR1POLBMAPT | |
| SCHEMBL7469830 | 0.83 | HTR6 (0.44) | ACHEBACE1MAPK1HTR6NPSR1 | |
| SCHEMBL7471400 | 0.83 | MAPT (0.42) | HTR6NPSR1POLBMAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |