Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 13/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469004 | 0.89 | ADRB3 (0.52) | HRH3ADRB3ADRB1ADRB2P2RY12 | |
| SCHEMBL7473044 | 0.89 | ADRB3 (0.52) | HRH3ADRB3ADRB1ADRB2P2RY12 | |
| SCHEMBL7136421 | 0.82 | ADRB3 (0.56) | ADRB3ADRB1ADRB2MAPT | |
| SCHEMBL7560376 | 0.80 | LMNA (0.56) | HRH3ADRB3ADRB1ADRB2P2RY12 | |
| SCHEMBL6301392 | 0.78 | HRH3 (0.47) | HRH3ADRB3ADRB1ADRB2P2RY12 | |
| SCHEMBL7469677 | 0.77 | ADRB1 (0.46) | HRH3ADRB3ADRB1ADRB2P2RY12 | |
| SCHEMBL7136547 | 0.77 | MAPT (0.58) | ADRB3ADRB1ADRB2MAPTLMNA | |
| SCHEMBL6953322 | 0.77 | HRH3 (0.44) | HRH3ADRB3ADRB1ADRB2P2RY12 | |
| SCHEMBL5202580 | 0.77 | ADRB3 (0.55) | ADRB3ADRB1ADRB2MAPTLMNA | |
| SCHEMBL7467963 | 0.76 | LMNA (0.44) | HRH3ADRB3ADRB1ADRB2P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-B1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI SYNTHELABO (FR) | 2002-08-14 | — | — | EP | disclosed |