Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7469837 | 0.99 | L3MBTL1 (0.35) | L3MBTL1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL7418934 | 0.90 | ACHE (0.40) | L3MBTL1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL7418930 | 0.90 | ACHE (0.40) | L3MBTL1MAPTALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8558971 | 0.89 | ACHE (0.39) | L3MBTL1MAPTALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8560377 | 0.88 | MAPK9 (0.36) | DRD3DRD2HTR2AACHE | |
| SCHEMBL8566938 | 0.83 | PPARD (0.33) | L3MBTL1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL8566943 | 0.83 | PPARD (0.33) | L3MBTL1MAPTALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8558943 | 0.81 | DRD2 (0.32) | HTR1ADRD3DGAT1DRD2PTGER3 | |
| Hydrochloric Acid SCHEMBL8558326 | 0.81 | DRD1 (0.35) | L3MBTL1MAPTKMT2APOLBMEN1 | |
| SCHEMBL7478828 | 0.80 | ESR1 (0.38) | L3MBTL1MAPTKMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | claimed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | claimed |