Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HRAS | P01112 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472733 | 0.89 | ALDH1A1 (0.39) | MAPTMEN1POLBKMT2AHRAS | |
| SCHEMBL7460611 | 0.88 | CNR1 (0.39) | MAPTMEN1POLBKMT2AHRAS | |
| SCHEMBL7469008 | 0.85 | MAPT (0.50) | MAPTMEN1POLBKMT2AHRAS | |
| SCHEMBL7468134 | 0.84 | MAPT (0.49) | MAPTMEN1POLBKMT2AHRAS | |
| SCHEMBL7470258 | 0.84 | HPGD (0.46) | MAPTMEN1POLBKMT2APRMT5 | |
| SCHEMBL7467413 | 0.82 | MAPT (0.37) | MAPTMEN1POLBKMT2AHRAS | |
| Hydrochloric Acid SCHEMBL7464634 | 0.82 | HRAS (0.45) | HRASESR1ESR2FLT3PRSS12 | |
| SCHEMBL7463241 | 0.81 | MAPT (0.42) | MAPTMEN1POLBKMT2AHRAS | |
| SCHEMBL7470426 | 0.80 | MAPT (0.49) | MAPTMEN1POLBKMT2AHRAS | |
| SCHEMBL7471355 | 0.80 | MAPT (0.43) | MAPTMEN1POLBKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |