Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.64 |
| ▸ | ADAM17 | P78536 | 20/20 | 0.64 |
| ▸ | MMP1 | P03956 | 16/20 | 0.64 |
| ▸ | MMP9 | P14780 | 6/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442494 | 0.93 | MMP13 (0.69) | MMP13ADAM17MMP1MMP9 | |
| SCHEMBL6506731 | 0.86 | MMP13 (0.80) | MMP13ADAM17MMP1MMP9 | |
| SCHEMBL6506359 | 0.83 | MMP13 (0.71) | MMP13ADAM17MMP1MMP9 | |
| SCHEMBL6501341 | 0.83 | ADAM17 (0.64) | MMP13ADAM17MMP1MMP9 | |
| SCHEMBL6501269 | 0.81 | MMP13 (0.61) | MMP13ADAM17MMP1MMP9 | |
| SCHEMBL6506884 | 0.81 | MMP13 (0.63) | MMP13ADAM17MMP1MMP9 | |
| SCHEMBL6503604 | 0.80 | MMP13 (0.60) | MMP13ADAM17MMP1MMP9 | |
| SCHEMBL3946136 | 0.80 | MMP1 (0.83) | MMP13ADAM17MMP1MMP9 | |
| Hydroxyamine SCHEMBL7489267 | 0.80 | MMP13 (0.60) | MMP13ADAM17MMP1MMP9 | |
| SCHEMBL6508439 | 0.80 | MMP13 (0.59) | MMP13ADAM17MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083112-A2 | METHOD FOR THE TREATMENT OF POLYCYSTIC KIDNEY DISEASE | WYETH HOLDINGS CORPORATION (US) | 2002-10-24 | — | — | WO | disclosed |