Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 6/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825809 | 0.82 | PDGFRB (0.44) | EGFRL3MBTL1PDGFRBALDH1A1HTT | |
| SCHEMBL7469896 | 0.81 | EGFR (0.46) | EGFRCSF1RPDGFRBALDH1A1MAPT | |
| SCHEMBL7472217 | 0.79 | EGFR (0.44) | EGFRCSF1RPDGFRBMAPTPDGFRA | |
| SCHEMBL7467291 | 0.79 | EGFR (0.44) | SMN1; SMN2EGFRCSF1RPDGFRBALDH1A1 | |
| SCHEMBL7469778 | 0.79 | MAPT (0.45) | SMN1; SMN2L3MBTL1ALDH1A1HTTTDP1 | |
| SCHEMBL7474845 | 0.78 | LMNA (0.55) | SMN1; SMN2EGFRCSF1RPDGFRBALDH1A1 | |
| SCHEMBL7466353 | 0.76 | EGFR (0.47) | SMN1; SMN2EGFRCSF1RPDGFRBALDH1A1 | |
| SCHEMBL7462398 | 0.75 | EGFR (0.47) | SMN1; SMN2EGFRL3MBTL1PDGFRBALDH1A1 | |
| SCHEMBL7472729 | 0.73 | EGFR (0.45) | SMN1; SMN2EGFRL3MBTL1PDGFRBALDH1A1 | |
| SCHEMBL30275314 | 0.72 | EGFR (0.54) | EGFRPDGFRBALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |